Homo sapiens Gene: BCLAF1 | |||||||||||||||||||||||
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Summary | |||||||||||||||||||||||
InnateDB Gene | IDBG-96919.6 | ||||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||
Gene Symbol | BCLAF1 | ||||||||||||||||||||||
Gene Name | BCL2-associated transcription factor 1 | ||||||||||||||||||||||
Synonyms | bK211L9.1; BTF | ||||||||||||||||||||||
Species | Homo sapiens | ||||||||||||||||||||||
Ensembl Gene | ENSG00000029363 | ||||||||||||||||||||||
Encoded Proteins |
BCL2-associated transcription factor 1
BCL2-associated transcription factor 1
BCL2-associated transcription factor 1
BCL2-associated transcription factor 1
BCL2-associated transcription factor 1
BCL2-associated transcription factor 1
BCL2-associated transcription factor 1
BCL2-associated transcription factor 1
BCL2-associated transcription factor 1
BCL2-associated transcription factor 1
BCL2-associated transcription factor 1
BCL2-associated transcription factor 1
BCL2-associated transcription factor 1
BCL2-associated transcription factor 1
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Protein Structure | |||||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||
Summary |
This gene encodes a transcriptional repressor that interacts with several members of the BCL2 family of proteins. Overexpression of this protein induces apoptosis, which can be suppressed by co-expression of BCL2 proteins. The protein localizes to dot-like structures throughout the nucleus, and redistributes to a zone near the nuclear envelope in cells undergoing apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||||
Genomic Location | Chromosome 6:136256863-136289851 | ||||||||||||||||||||||
Strand | Reverse strand | ||||||||||||||||||||||
Band | q23.3 | ||||||||||||||||||||||
Transcripts | |||||||||||||||||||||||
Interactions | |||||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 54 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||||
Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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Cross-References | |||||||||||||||||||||||
SwissProt | |||||||||||||||||||||||
TrEMBL | H0YF00 | ||||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||||
Entrez Gene | 9774 | ||||||||||||||||||||||
UniGene | Hs.486542 Hs.601398 Hs.617546 Hs.627320 Hs.710172 Hs.718334 | ||||||||||||||||||||||
RefSeq | NM_001077440 NM_001077441 NM_001301038 NM_014739 XM_005267236 XM_005267239 | ||||||||||||||||||||||
HUGO | HGNC:16863 | ||||||||||||||||||||||
OMIM | 612588 | ||||||||||||||||||||||
CCDS | CCDS47485 CCDS47486 CCDS5177 CCDS75525 | ||||||||||||||||||||||
HPRD | 16544 | ||||||||||||||||||||||
IMGT | |||||||||||||||||||||||
EMBL | AL121713 | ||||||||||||||||||||||
GenPept | |||||||||||||||||||||||
RNA Seq Atlas | 9774 | ||||||||||||||||||||||