Version 5.4
Homo sapiens Gene: HIVEP2
Summary
InnateDB Gene IDBG-97259.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HIVEP2
Gene Name human immunodeficiency virus type I enhancer binding protein 2
Synonyms HIV-EP2; MBP-2; MIBP1; SHN2; ZAS2; ZNF40B
Species Homo sapiens
Ensembl Gene ENSG00000010818
Encoded Proteins
IDBP-97261
human immunodeficiency virus type I enhancer binding protein 2
IDBP-97263
human immunodeficiency virus type I enhancer binding protein 2
IDBP-97265
human immunodeficiency virus type I enhancer binding protein 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of a family of closely related, large, zinc finger-containing transcription factors. The encoded protein regulates transcription by binding to regulatory regions of various cellular and viral genes that maybe involved in growth, development and metastasis. The protein contains the ZAS domain comprised of two widely separated regions of zinc finger motifs, a stretch of highly acidic amino acids and a serine/threonine-rich sequence. [provided by RefSeq, Nov 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:142751467-142945201
Strand Reverse strand
Band q24.2
Transcripts
ENST00000367604 ENSP00000356576
ENST00000012134 ENSP00000012134
ENST00000367603 ENSP00000356575
ENST00000474532
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000015501
View Gene Order
ENSBTAG00000001146
Not yet available
Cross-References
SwissProt P31629
TrEMBL B4DKE9
UniProt Splice Variant
Entrez Gene 3097
UniGene Hs.510172
RefSeq NM_006734 XM_005266957
HUGO HGNC:4921
OMIM 143054
CCDS CCDS43510
HPRD 00881
IMGT
EMBL AF153836 AK296531 AL023584 M60119 M61744 X65644
GenPept AAA36202 AAB88218 AAF81365 BAG59161 CAA19042 CAA46596
RNA Seq Atlas 3097

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca