Version 5.4
| Homo sapiens Gene: PIK3R3 | |||||||||||||||||||||||
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| Summary | |||||||||||||||||||||||
| InnateDB Gene | IDBG-98070.6 | ||||||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||
| Gene Symbol | PIK3R3 | ||||||||||||||||||||||
| Gene Name | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | ||||||||||||||||||||||
| Synonyms | p55; p55-GAMMA | ||||||||||||||||||||||
| Species | Homo sapiens | ||||||||||||||||||||||
| Ensembl Gene | ENSG00000117461 | ||||||||||||||||||||||
| Encoded Proteins |
phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
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| Protein Structure | |||||||||||||||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||
| Entrez Gene | |||||||||||||||||||||||
| Summary | Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs. | ||||||||||||||||||||||
| Gene Information | |||||||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||||||
| Genomic Location | Chromosome 1:46040140-46133036 | ||||||||||||||||||||||
| Strand | Reverse strand | ||||||||||||||||||||||
| Band | p34.1 | ||||||||||||||||||||||
| Transcripts | |||||||||||||||||||||||
| Interactions | |||||||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 66 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||||||||
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Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||||||||||||||||
| NETPATH |
Alpha6Beta4Integrin pathway
EGFR1 pathway
IL2 pathway
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| REACTOME |
PIP3 activates AKT signaling pathway
DAP12 signaling pathway
DAP12 interactions pathway
Regulation of signaling by CBL pathway
Interleukin receptor SHC signaling pathway
Interleukin-3, 5 and GM-CSF signaling pathway
Interleukin-2 signaling pathway
Interleukin-7 signaling pathway
CD28 dependent PI3K/Akt signaling pathway
CD28 co-stimulation pathway
Costimulation by the CD28 family pathway
GPVI-mediated activation cascade pathway
PI3K/AKT activation pathway
GAB1 signalosome pathway
Signaling by EGFR pathway
G alpha (q) signalling events pathway
Gastrin-CREB signalling pathway via PKC and MAPK pathway
G beta:gamma signalling through PI3Kgamma pathway
G alpha (12/13) signalling events pathway
PI3K events in ERBB4 signaling pathway
Signaling by ERBB4 pathway
PI3K events in ERBB2 signaling pathway
Signaling by ERBB2 pathway
PI-3K cascade pathway
Signaling by FGFR pathway
Signaling by SCF-KIT pathway
Downstream signal transduction pathway
Signaling by PDGF pathway
Synthesis of PIPs at the plasma membrane pathway
Constitutive PI3K/AKT Signaling in Cancer pathway
Signaling by FGFR in disease pathway
Signalling by NGF pathway
Signaling by EGFR in Cancer pathway
Downstream signaling of activated FGFR pathway
Metabolism of lipids and lipoproteins pathway
Role of LAT2/NTAL/LAB on calcium mobilization pathway
Cytokine Signaling in Immune system pathway
Signaling by GPCR pathway
Innate Immune System pathway
Platelet activation, signaling and aggregation pathway
G-protein beta:gamma signalling pathway
Fc epsilon receptor (FCERI) signaling pathway
Signal Transduction pathway
GPCR downstream signaling pathway
Adaptive Immune System pathway
Immune System pathway
Signaling by Interleukins pathway
NGF signalling via TRKA from the plasma membrane pathway
PI Metabolism pathway
Phospholipid metabolism pathway
PI3K/AKT Signaling in Cancer pathway
Metabolism pathway
Signaling by the B Cell Receptor (BCR) pathway
Downstream signaling events of B Cell Receptor (BCR) pathway
Disease pathway
Hemostasis pathway
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| KEGG |
Regulation of actin cytoskeleton pathway
mTOR signaling pathway pathway
Acute myeloid leukemia pathway
VEGF signaling pathway pathway
Fc epsilon RI signaling pathway pathway
Colorectal cancer pathway
Non-small cell lung cancer pathway
ErbB signaling pathway pathway
Renal cell carcinoma pathway
Apoptosis pathway
Melanoma pathway
Endometrial cancer pathway
Leukocyte transendothelial migration pathway
Glioma pathway
Small cell lung cancer pathway
Phosphatidylinositol signaling system pathway
Insulin signaling pathway pathway
B cell receptor signaling pathway pathway
Prostate cancer pathway
Focal adhesion pathway
T cell receptor signaling pathway pathway
Toll-like receptor signaling pathway pathway
Jak-STAT signaling pathway pathway
Type II diabetes mellitus pathway
Natural killer cell mediated cytotoxicity pathway
Chronic myeloid leukemia pathway
Pancreatic cancer pathway
Fc gamma R-mediated phagocytosis pathway
Neurotrophin signaling pathway pathway
Chemokine signaling pathway pathway
Pathways in cancer pathway
Progesterone-mediated oocyte maturation pathway
Aldosterone-regulated sodium reabsorption pathway
Amoebiasis pathway
Bacterial invasion of epithelial cells pathway
Chagas disease (American trypanosomiasis) pathway
Osteoclast differentiation pathway
Toxoplasmosis pathway
Carbohydrate digestion and absorption pathway
Hepatitis C pathway
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| INOH | |||||||||||||||||||||||
| PID NCI | |||||||||||||||||||||||
| Cross-References | |||||||||||||||||||||||
| SwissProt | |||||||||||||||||||||||
| TrEMBL | |||||||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||||||
| Entrez Gene | |||||||||||||||||||||||
| UniGene | Hs.609132 Hs.655387 | ||||||||||||||||||||||
| RefSeq | NM_001114172 NM_003629 XM_005271290 | ||||||||||||||||||||||
| HUGO | |||||||||||||||||||||||
| OMIM | |||||||||||||||||||||||
| CCDS | CCDS529 | ||||||||||||||||||||||
| HPRD | 05831 | ||||||||||||||||||||||
| IMGT | |||||||||||||||||||||||
| EMBL | |||||||||||||||||||||||
| GenPept | |||||||||||||||||||||||
| RNA Seq Atlas | |||||||||||||||||||||||