Version 5.4
Homo sapiens Gene: QKI
Summary
InnateDB Gene IDBG-98868.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol QKI
Gene Name QKI, KH domain containing, RNA binding
Synonyms Hqk; hqkI; QK; QK1; QK3
Species Homo sapiens
Ensembl Gene ENSG00000112531
Encoded Proteins
IDBP-98870
QKI, KH domain containing, RNA binding
IDBP-98872
QKI, KH domain containing, RNA binding
IDBP-98874
QKI, KH domain containing, RNA binding
IDBP-98876
QKI, KH domain containing, RNA binding
IDBP-246291
QKI, KH domain containing, RNA binding
IDBP-388222
QKI, KH domain containing, RNA binding
IDBP-388223
QKI, KH domain containing, RNA binding
IDBP-598415
QKI, KH domain containing, RNA binding
IDBP-595027
QKI, KH domain containing, RNA binding
IDBP-586722
QKI, KH domain containing, RNA binding
IDBP-586073
QKI, KH domain containing, RNA binding
IDBP-583355
QKI, KH domain containing, RNA binding
IDBP-591097
QKI, KH domain containing, RNA binding
IDBP-597492
QKI, KH domain containing, RNA binding
IDBP-595505
QKI, KH domain containing, RNA binding
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is an RNA-binding protein that regulates pre-mRNA splicing, export of mRNAs from the nucleus, protein translation, and mRNA stability. The encoded protein is involved in myelinization and oligodendrocyte differentiation and may play a role in schizophrenia. Four transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2011]
The protein encoded by this gene is an RNA-binding protein that regulates pre-mRNA splicing, export of mRNAs from the nucleus, protein translation, and mRNA stability. The encoded protein is involved in myelinization and oligodendrocyte differentiation and may play a role in schizophrenia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:163414000-163578596
Strand Forward strand
Band q26
Transcripts
ENST00000361752 ENSP00000355094
ENST00000361758 ENSP00000354951
ENST00000275262 ENSP00000275262
ENST00000361195 ENSP00000354867
ENST00000392127 ENSP00000375973
ENST00000453779 ENSP00000408775
ENST00000424802 ENSP00000408382
ENST00000545607 ENSP00000437867
ENST00000544436 ENSP00000443690
ENST00000537041 ENSP00000440991
ENST00000537124 ENSP00000443106
ENST00000545346 ENSP00000441252
ENST00000544823 ENSP00000440599
ENST00000537883 ENSP00000441773
ENST00000540719
ENST00000544361 ENSP00000442848
ENST00000541696
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 67 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 67 [view]
Protein-Protein 67 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0017124 SH3 domain binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0001570 vasculogenesis
GO:0006397 mRNA processing
GO:0006417 regulation of translation
GO:0007286 spermatid development
GO:0008366 axon ensheathment
GO:0008380 RNA splicing
GO:0010628 positive regulation of gene expression
GO:0042552 myelination
GO:0042692 muscle cell differentiation
GO:0042759 long-chain fatty acid biosynthetic process
GO:0051028 mRNA transport
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000062078
View Gene Order
ENSBTAG00000011593
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 9444
UniGene Hs.510324 Hs.606284 Hs.609810 Hs.611956 Hs.623513 Hs.703151 Hs.708585
RefSeq NM_001301085 NM_006775 NM_206853 NM_206854 NM_206855 XM_005267224
HUGO HGNC:21100
OMIM 609590
CCDS CCDS43525 CCDS5285 CCDS5286 CCDS5287 CCDS75546
HPRD 06691
IMGT
EMBL
GenPept
RNA Seq Atlas 9444

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca