Version 5.4
Homo sapiens Gene: DACT2
Summary
InnateDB Gene IDBG-99193.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DACT2
Gene Name dapper, antagonist of beta-catenin, homolog 2 (Xenopus laevis)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000164488
Encoded Proteins
IDBP-99195
dapper, antagonist of beta-catenin, homolog 2 (Xenopus laevis)
IDBP-99197
dapper, antagonist of beta-catenin, homolog 2 (Xenopus laevis)
IDBP-813042
dishevelled-binding antagonist of beta-catenin 2
IDBP-813043
dishevelled-binding antagonist of beta-catenin 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 6:168292830-168319754
Strand Reverse strand
Band q27
Transcripts
ENST00000366796 ENSP00000355761
ENST00000366795 ENSP00000355760
ENST00000610183 ENSP00000476573
ENST00000607983 ENSP00000476434
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.
Predicted by orthology
Total 19 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005080 protein kinase C binding
GO:0005515 protein binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0051018 protein kinase A binding
GO:0070097 delta-catenin binding
Biological Process
GO:0002244 hematopoietic progenitor cell differentiation
GO:0003382 epithelial cell morphogenesis
GO:0007162 negative regulation of cell adhesion
GO:0043588 skin development
GO:0072061 inner medullary collecting duct development
GO:1900108 negative regulation of nodal signaling pathway
Cellular Component
GO:0005739 mitochondrion
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000048826
View Gene Order
ENSBTAG00000031532
Not yet available
Pathways
NETPATH
REACTOME
KEGG
INOH
PID NCI
tgfbrpathway
TGF-beta receptor signaling
Cross-References
SwissProt Q5SW24
TrEMBL
UniProt Splice Variant
Entrez Gene 168002
UniGene Hs.673059
RefSeq NM_001286350 NM_001286351 NM_214462
HUGO HGNC:21231
OMIM 608966
CCDS CCDS47519 CCDS69241 CCDS75554
HPRD
IMGT
EMBL AF318336 AL606970 BC092498 BC111764 BC111790
GenPept AAH92498 AAI11765 AAI11791 AAL55843 CAI14850
RNA Seq Atlas 168002

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca