Homo sapiens Gene: SRSF11
Summary
InnateDB Gene IDBG-99636.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SRSF11
Gene Name serine/arginine-rich splicing factor 11
Synonyms dJ677H15.2; NET2; p54; SFRS11
Species Homo sapiens
Ensembl Gene ENSG00000116754
Encoded Proteins
serine/arginine-rich splicing factor 11
serine/arginine-rich splicing factor 11
serine/arginine-rich splicing factor 11
serine/arginine-rich splicing factor 11
serine/arginine-rich splicing factor 11
serine/arginine-rich splicing factor 11
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes 54-kD nuclear protein that contains an arginine/serine-rich region similar to segments found in pre-mRNA splicing factors. Although the function of this protein is not yet known, structure and immunolocalization data suggest that it may play a role in pre-mRNA processing. Alternative splicing results in multiple transcript variants encoding different proteins. In addition, a pseudogene of this gene has been found on chromosome 12.[provided by RefSeq, Sep 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:70205682-70253052
Strand Forward strand
Band p31.1
Transcripts
ENST00000370951 ENSP00000359989
ENST00000370950 ENSP00000359988
ENST00000370949 ENSP00000359987
ENST00000395136 ENSP00000378568
ENST00000463877
ENST00000475204 ENSP00000474372
ENST00000473950 ENSP00000474149
ENST00000469170
ENST00000486667
ENST00000481648
ENST00000463116
ENST00000484162
ENST00000463859
ENST00000460795
ENST00000461935
ENST00000489188
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 64 experimentally validated interaction(s) in this database.
Experimentally validated
Total 64 [view]
Protein-Protein 59 [view]
Protein-DNA 5 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0000398 mRNA splicing, via spliceosome
GO:0006366 transcription from RNA polymerase II promoter
GO:0006369 termination of RNA polymerase II transcription
GO:0006397 mRNA processing
GO:0006406 mRNA export from nucleus
GO:0008380 RNA splicing
GO:0010467 gene expression
GO:0031124 mRNA 3'-end processing
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
TSLP pathway
REACTOME
mRNA 3'-end processing pathway
mRNA Splicing - Major Pathway pathway
Transport of Mature mRNA derived from an Intron-Containing Transcript pathway
Processing of Capped Intron-Containing Pre-mRNA pathway
Cleavage of Growing Transcript in the Termination Region pathway
RNA Polymerase II Transcription Termination pathway
RNA Polymerase II Transcription pathway
Transport of Mature Transcript to Cytoplasm pathway
mRNA Splicing pathway
Gene Expression pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.479693 Hs.628182
RefSeq NM_001190987 NM_004768 XM_005271338 XM_005271339 XM_006711037 XM_006711038
HUGO
OMIM
CCDS CCDS53332 CCDS647
HPRD 03599
IMGT
EMBL
GenPept
RNA Seq Atlas