Version 5.4
Mus musculus Protein: Tor2a
Summary
InnateDB Protein IDBP-161441.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tor2a
Protein Name torsin family 2, member A
Synonyms Prosalusin;
Species Mus musculus
Ensembl Protein ENSMUSP00000009707
InnateDB Gene IDBG-161439 (Tor2a)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Endoplasmic reticulum lumen {ECO:0000269PubMed:20015956}.
Disease Associations
Tissue Specificity Expressed at similar levels in liver, muscle and brain (at protein level). {ECO:0000269PubMed:20015956}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005524 ATP binding
Biological Process
GO:0051085 chaperone mediated protein folding requiring cofactor
GO:0051260 protein homooligomerization
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005788 endoplasmic reticulum lumen
Protein Structure and Domains
PDB ID MGI:1353596
InterPro IPR001270 ClpA/B family
IPR010448 Torsin
IPR017378 Torsin, subgroup
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF06309
PRINTS PR00300
PIRSF PIRSF038079
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8R1J9
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 30933
UniGene Mm.200695
RefSeq NP_690013
MGI ID
MGI Symbol Tor2a
OMIM
CCDS CCDS15929
HPRD
IMGT
EMBL AK003976 AK162719 AK170979 AK171247 BC003466 BC023085 BC024469
GenPept AAH03466 AAH23085 AAH24469 BAE37036 BAE42156 BAE42340 BAE43155

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca