Version 5.4
Mus musculus Protein: Det1
Summary
InnateDB Protein IDBP-193479.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Det1
Protein Name de-etiolated homolog 1 (Arabidopsis)
Synonyms 2610034H20Rik;
Species Mus musculus
Ensembl Protein ENSMUSP00000032839
InnateDB Gene IDBG-193477 (Det1)
Protein Structure
UniProt Annotation
Function Component of the E3 ubiquitin ligase DCX DET1-COP1 complex, which is required for ubiquitination and subsequent degradation of target proteins. The complex is involved in JUN ubiquitination and degradation (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005575 cellular_component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID MGI:1923625
InterPro IPR019138 De-etiolated protein 1, Det1
PFAM PF09737
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9D0A0
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 76375
UniGene Mm.250541
RefSeq NP_083861
MGI ID
MGI Symbol Det1
OMIM
CCDS CCDS21375
HPRD
IMGT
EMBL AK011666 BC031930
GenPept AAH31930 BAB27766

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca