InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: CELF1

Summary

InnateDB Protein

IDBP-239851.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CELF1

Protein Name

CUGBP, Elav-like family member 1

Synonyms

BRUNOL2; CUG-BP; CUGBP; CUGBP1; EDEN-BP; hNab50; NAB50; NAPOR;

Species

Homo sapiens

Ensembl Protein

ENSP00000378705

InnateDB Gene

IDBG-43515 (CELF1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 22 experimentally validated interaction(s) in this database.

Experimentally validated
Total	22 [view]
Protein-Protein	20 [view]
Protein-DNA	0
Protein-RNA	2 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0000900	translation repressor activity, nucleic acid binding
GO:0003676	nucleic acid binding
GO:0003723	RNA binding
GO:0003729	mRNA binding
GO:0005515	protein binding
GO:0042835	BRE binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0006376	mRNA splice site selection
GO:0006397	mRNA processing
GO:0007281	germ cell development
GO:0009790	embryo development
GO:0016246	RNA interference
GO:0017148	negative regulation of translation
GO:0043484	regulation of RNA splicing

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0016020	membrane
GO:0030529	ribonucleoprotein complex

Protein Structure and Domains

PDB ID

InterPro

IPR000504 RNA recognition motif domain

PFAM

PF00076

PRINTS

PIRSF

SMART

SM00360

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-Q92879

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

RefSeq

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

AB210019 AC090559 AF248648 AF267533 AF267534 AJ007988 AK304430 BC031079 CH471064 U63289

GenPept

AAC50895 AAF78955 AAF78956 AAF86230 AAH31079 BAE06101 BAG65257 CAC20566 EAW67909 EAW67912

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1)

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca