Homo sapiens Protein: SPTBN4
Summary
InnateDB Protein IDBP-246499.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SPTBN4
Protein Name spectrin, beta, non-erythrocytic 4
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000375877
InnateDB Gene IDBG-51618 (SPTBN4)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 25 experimentally validated interaction(s) in this database.
Experimentally validated
Total 25 [view]
Protein-Protein 24 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005200 structural constituent of cytoskeleton
GO:0005515 protein binding
GO:0005543 phospholipid binding
GO:0019902 phosphatase binding
GO:0030506 ankyrin binding
GO:0030507 spectrin binding
Biological Process
GO:0002028 regulation of sodium ion transport
GO:0007016 cytoskeletal anchoring at plasma membrane
GO:0007409 axonogenesis
GO:0007411 axon guidance
GO:0007605 sensory perception of sound
GO:0007628 adult walking behavior
GO:0010459 negative regulation of heart rate
GO:0016192 vesicle-mediated transport
GO:0019226 transmission of nerve impulse
GO:0021952 central nervous system projection neuron axonogenesis
GO:0033135 regulation of peptidyl-serine phosphorylation
GO:0045162 clustering of voltage-gated sodium channels
GO:0051693 actin filament capping
GO:0061337 cardiac conduction
GO:0090002 establishment of protein localization to plasma membrane
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005912 adherens junction
GO:0008091 spectrin
GO:0016020 membrane
GO:0016363 nuclear matrix
GO:0016605 PML body
GO:0033268 node of Ranvier
GO:0043025 neuronal cell body
GO:0043194 axon initial segment
GO:0043203 axon hillock
GO:0070852 cell body fiber
Protein Structure and Domains
PDB ID
InterPro IPR002017 Spectrin repeat
IPR018159 Spectrin/alpha-actinin
PFAM PF00435
PRINTS
PIRSF
SMART SM00150
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9H254
PhosphoSite PhosphoSite-Q9H254
TrEMBL Q9UFA1
UniProt Splice Variant
Entrez Gene 57731
UniGene Hs.595840
RefSeq NP_079489
HUGO HGNC:14896
OMIM 606214
CCDS CCDS42569
HPRD 09372
IMGT
EMBL AB046862 AC020929 AF082075 AF311855 AF311856 AL133093 AY004226 AY004227
GenPept AAF93171 AAF93172 AAF93173 AAG38874 AAG42473 AAG42474 BAB13468 CAB61407