Version 5.4
Homo sapiens Protein: SHC1
Summary
InnateDB Protein IDBP-388791.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SHC1
Protein Name SHC (Src homology 2 domain containing) transforming protein 1
Synonyms SHC; SHCA;
Species Homo sapiens
Ensembl Protein ENSP00000396162
InnateDB Gene IDBG-103007 (SHC1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 311 experimentally validated interaction(s) in this database.
They are also associated with 39 interaction(s) predicted by orthology.
Experimentally validated
Total 311 [view]
Protein-Protein 309 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 39 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0035556 intracellular signal transduction
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR006019 Phosphotyrosine interaction domain, Shc-like
IPR006020 PTB/PI domain
PFAM PF00640
PF14719
PRINTS PR00629
PIRSF
SMART SM00462
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q8NFT0
UniProt Splice Variant
Entrez Gene 6464
UniGene Hs.743646
RefSeq
HUGO HGNC:10840
OMIM 600560
CCDS
HPRD 02780
IMGT
EMBL AF455141 AL451085
GenPept AAM61860

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca