InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PDHB

Summary

InnateDB Protein

IDBP-476091.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PDHB

Protein Name

pyruvate dehydrogenase (lipoamide) beta

Synonyms

PDHBD; PDHE1-B; PHE1B;

Species

Homo sapiens

Ensembl Protein

ENSP00000418448

InnateDB Gene

IDBG-42225 (PDHB)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 48 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	48 [view]
Protein-Protein	48 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004739	pyruvate dehydrogenase (acetyl-transferring) activity

Biological Process

GO:0006086	acetyl-CoA biosynthetic process from pyruvate
GO:0008152	metabolic process
GO:0055114	oxidation-reduction process

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR005475 Transketolase-like, pyrimidine-binding domain
IPR005476 Transketolase, C-terminal
IPR009014 Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II
IPR029061 Thiamin diphosphate-binding fold

PFAM

PF02779
PF02780

PRINTS

PIRSF

SMART

SM00861

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite