InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: NR1I3

Summary

InnateDB Protein

IDBP-481161.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NR1I3

Protein Name

nuclear receptor subfamily 1, group I, member 3

Synonyms

CAR; CAR1; MB67;

Species

Homo sapiens

Ensembl Protein

ENSP00000421588

InnateDB Gene

IDBG-104246 (NR1I3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.

Experimentally validated
Total	18 [view]
Protein-Protein	18 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	9 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0003707	steroid hormone receptor activity
GO:0004887	thyroid hormone receptor activity

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0030522	intracellular receptor signaling pathway
GO:0043401	steroid hormone mediated signaling pathway

Cellular Component

GO:0005634

nucleus

Protein Structure and Domains

PDB ID

InterPro

IPR000536 Nuclear hormone receptor, ligand-binding, core
IPR001723 Steroid hormone receptor
IPR001728 Thyroid hormone receptor
IPR008946 Nuclear hormone receptor, ligand-binding

PFAM

PF00104

PRINTS

PR00398
PR00546

PIRSF

SMART

SM00430

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt