Version 5.4
Homo sapiens Protein: PDHB
Summary
InnateDB Protein IDBP-484493.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PDHB
Protein Name pyruvate dehydrogenase (lipoamide) beta
Synonyms PDHBD; PDHE1-B; PHE1B;
Species Homo sapiens
Ensembl Protein ENSP00000419580
InnateDB Gene IDBG-42225 (PDHB)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 48 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 48 [view]
Protein-Protein 48 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity
Biological Process
GO:0006086 acetyl-CoA biosynthetic process from pyruvate
GO:0055114 oxidation-reduction process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR005475 Transketolase-like, pyrimidine-binding domain
IPR029061 Thiamin diphosphate-binding fold
PFAM PF02779
PRINTS
PIRSF
SMART SM00861
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F8WF02
UniProt Splice Variant
Entrez Gene 5162
UniGene Hs.613823
RefSeq
HUGO HGNC:8808
OMIM 179060
CCDS
HPRD 01530
IMGT
EMBL AC135507
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca