Version 5.4
Homo sapiens Protein: BSCL2
Summary
InnateDB Protein IDBP-51627.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BSCL2
Protein Name Berardinelli-Seip congenital lipodystrophy 2 (seipin)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000354032
InnateDB Gene IDBG-51625 (BSCL2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0008219 cell death
GO:0016042 lipid catabolic process
GO:0019915 lipid storage
GO:0034389 lipid particle organization
GO:0045444 fat cell differentiation
GO:0050995 negative regulation of lipid catabolic process
Cellular Component
GO:0030176 integral component of endoplasmic reticulum membrane
Protein Structure and Domains
PDB ID
InterPro IPR009617 Adipose-regulatory protein, Seipin
PFAM PF06775
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q96G97
PhosphoSite PhosphoSite-Q96G97
TrEMBL F8W7Q8
UniProt Splice Variant
Entrez Gene 26580
UniGene Hs.732344
RefSeq NP_001116427
HUGO HGNC:15832
OMIM 606158
CCDS CCDS44627
HPRD 05858
IMGT
EMBL AF052149 AK027524 AK075317 AP001458 BC004911 BC012140 BC041640 BC093048 CH471076
GenPept AAH04911 AAH12140 AAH41640 AAH93048 BAB55175 BAC11543 EAW74070 EAW74074 EAW74075 EAW74080 EAW74081

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca