Version 5.4
Homo sapiens Protein: SPINK7
Summary
InnateDB Protein IDBP-52437.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SPINK7
Protein Name serine peptidase inhibitor, Kazal type 7 (putative)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000274565
InnateDB Gene IDBG-52435 (SPINK7)
Protein Structure
UniProt Annotation
Function Probable serine protease inhibitor.
Subcellular Localization Secreted {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004867 serine-type endopeptidase inhibitor activity
GO:0005515 protein binding
Biological Process
GO:0010951 negative regulation of endopeptidase activity
Cellular Component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID
InterPro IPR002350 Kazal domain
PFAM PF00050
PF07648
PRINTS
PIRSF
SMART SM00280
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P58062
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 84651
UniGene Hs.244569
RefSeq NP_115955
HUGO HGNC:24643
OMIM
CCDS CCDS4289
HPRD 16850
IMGT
EMBL AF268198 AY359072 BC109385 BC110067
GenPept AAI09386 AAI10068 AAK27795 AAQ89431

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca