InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Kcnq2

Summary

InnateDB Protein

IDBP-539537.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Kcnq2

Protein Name

potassium voltage-gated channel, subfamily Q, member 2

Synonyms

HNSPC; KQT2; Nmf134;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000123488

InnateDB Gene

IDBG-213954 (Kcnq2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005216	ion channel activity
GO:0005251	delayed rectifier potassium channel activity
GO:0005267	potassium channel activity

Biological Process

GO:0006811	ion transport
GO:0019226	transmission of nerve impulse
GO:0055085	transmembrane transport
GO:0071805	potassium ion transmembrane transport

Cellular Component

GO:0008076	voltage-gated potassium channel complex
GO:0016020	membrane

Protein Structure and Domains

PDB ID

MGI:1309503

InterPro

IPR003091 Potassium channel
IPR003937 Potassium channel, voltage dependent, KCNQ
IPR005821 Ion transport domain
IPR013099 Two pore domain potassium channel domain
IPR013821 Potassium channel, voltage dependent, KCNQ, C-terminal
IPR020969 Ankyrin-G binding site

PFAM

PF00520
PF07885
PF03520
PF11956

PRINTS

PR00169
PR01459

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite