Version 5.4
Homo sapiens Protein: MYL4
Summary
InnateDB Protein IDBP-55863.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MYL4
Protein Name myosin, light chain 4, alkali; atrial, embryonic
Synonyms ALC1; AMLC; GT1;
Species Homo sapiens
Ensembl Protein ENSP00000347055
InnateDB Gene IDBG-55861 (MYL4)
Protein Structure
UniProt Annotation
Function Regulatory light chain of myosin. Does not bind calcium.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003785 actin monomer binding
GO:0005509 calcium ion binding
GO:0032038 myosin II heavy chain binding
GO:0051015 actin filament binding
Biological Process
GO:0002026 regulation of the force of heart contraction
GO:0030049 muscle filament sliding
GO:0032781 positive regulation of ATPase activity
GO:0060048 cardiac muscle contraction
Cellular Component
GO:0005829 cytosol
GO:0016459 myosin complex
GO:0031672 A band
Protein Structure and Domains
PDB ID
InterPro IPR002048 EF-hand domain
PFAM PF00036
PF13202
PF13405
PRINTS
PIRSF
SMART SM00054
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P12829
PhosphoSite PhosphoSite-P12829
TrEMBL I3L1K6
UniProt Splice Variant
Entrez Gene 4635
UniGene Hs.463300
RefSeq NP_001002841
HUGO HGNC:7585
OMIM 160770
CCDS CCDS11510
HPRD 01176
IMGT
EMBL AC068234 AC087649 AF116676 BC030228 CH471231 M20641 M24121 M36172 M37069 M37070 M37071 M37072 M37073 M37074 X13955 X58851 X58852 X58853 X58854
GenPept AAA36319 AAA59856 AAA59858 AAA59891 AAF71096 AAH30228 CAA32137 CAA41655 EAW57684 EAW57685

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca