InnateDB Protein
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IDBP-56546.7
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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NFE2L1
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Protein Name
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nuclear factor (erythroid-derived 2)-like 1
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Synonyms
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LCR-F1; NRF1; TCF11;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000350072
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InnateDB Gene
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IDBG-56544 (NFE2L1)
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Protein Structure
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Function |
Activates erythroid-specific, globin gene expression.
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Subcellular Localization |
Endoplasmic reticulum membrane {ECO:0000269PubMed:16687406}; Single-pass type II membrane protein {ECO:0000269PubMed:16687406}. Nucleus {ECO:0000255PROSITE-ProRule:PRU00978, ECO:0000269PubMed:16687406}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 25 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
25
[view]
|
Protein-Protein |
23
[view]
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Protein-DNA |
2
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR004827
Basic-leucine zipper domain
IPR008917
Transcription factor, Skn-1-like, DNA-binding domain
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PFAM |
PF00170
PF07716
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PRINTS |
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PIRSF |
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SMART |
SM00338
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TIGRFAMs |
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Modification |
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SwissProt |
Q14494
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PhosphoSite |
PhosphoSite-Q14494
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TrEMBL |
J3QR31
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UniProt Splice Variant |
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Entrez Gene |
4779
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UniGene |
Hs.740157
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RefSeq |
XP_005257469
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HUGO |
HGNC:7781
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OMIM |
163260
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CCDS |
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HPRD |
01223
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IMGT |
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EMBL |
AC004477
BC010623
CH471109
L24123
U08853
X77366
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GenPept |
AAA20466
AAH10623
CAA54555
EAW94762
EAW94763
EAW94764
EAW94765
EAW94766
EAW94767
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