Version 5.4
Homo sapiens Protein: FAM188A
Summary
InnateDB Protein IDBP-57364.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FAM188A
Protein Name family with sequence similarity 188, member A
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000277632
InnateDB Gene IDBG-57362 (FAM188A)
Protein Structure
UniProt Annotation
Function May have pro-apoptotic function. Overexpression significantly inhibits cell proliferation in several tumor cell lines.
Subcellular Localization Nucleus {ECO:0000269PubMed:12054670}.
Disease Associations
Tissue Specificity Highly expressed in heart, skeletal muscle, and kidney, with weak expression in liver and brain. {ECO:0000269PubMed:12054670}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
Biological Process
GO:0006915 apoptotic process
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9H8M7
PhosphoSite PhosphoSite-Q9H8M7
TrEMBL X6RC30
UniProt Splice Variant
Entrez Gene 80013
UniGene Hs.720895
RefSeq NP_079224
HUGO HGNC:23578
OMIM 611649
CCDS CCDS7110
HPRD 10702
IMGT
EMBL AB014761 AF063600 AF176916 AK023459 AL590439 AL833873 BC020605 BC061585 BC067799 CH471072 CR457315
GenPept AAG43159 AAH20605 AAH61585 AAH67799 AAQ13660 BAB14582 BAB87802 CAD38730 CAG33596 CAI13817 CAI13818 CAI13819 CAI13820 EAW86233 EAW86234

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca