InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SDHD

Summary

InnateDB Protein

IDBP-585713.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SDHD

Protein Name

succinate dehydrogenase complex, subunit D, integral membrane protein

Synonyms

CBT1; CII-4; CWS3; cybS; PGL; PGL1; QPs3; SDH4;

Species

Homo sapiens

Ensembl Protein

ENSP00000436669

InnateDB Gene

IDBG-71313 (SDHD)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	0
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000104	succinate dehydrogenase activity
GO:0009055	electron carrier activity
GO:0020037	heme binding
GO:0046872	metal ion binding
GO:0048039	ubiquinone binding

Biological Process

GO:0006099	tricarboxylic acid cycle
GO:0022904	respiratory electron transport chain
GO:0044237	cellular metabolic process
GO:0044281	small molecule metabolic process

Cellular Component

GO:0005739	mitochondrion
GO:0005740	mitochondrial envelope
GO:0005743	mitochondrial inner membrane
GO:0005749	mitochondrial respiratory chain complex II
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR007992 Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, CybS

PFAM

PF05328

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

RefSeq

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

AB006202 AB026906 AK075360 AP002007 BC005263 BC009574 BC012603 BC015188 BC015992 BC022350 BC070307 BC071755 BC071756 BT007238 CH471065 CR456932

GenPept

AAH05263 AAH09574 AAH12603 AAH15188 AAH15992 AAH22350 AAH70307 AAH71755 AAH71756 AAP35902 BAA22054 BAA81889 BAG52120 CAG33213 EAW67181

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1)

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca