Version 5.4
Homo sapiens Protein: ARHGAP11A
Summary
InnateDB Protein IDBP-597375.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ARHGAP11A
Protein Name Rho GTPase activating protein 11A
Synonyms GAP (1-12);
Species Homo sapiens
Ensembl Protein ENSP00000440073
InnateDB Gene IDBG-5147 (ARHGAP11A)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 3 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005096 GTPase activator activity
Biological Process
GO:0007165 signal transduction
GO:0007264 small GTPase mediated signal transduction
GO:0043547 positive regulation of GTPase activity
GO:0051056 regulation of small GTPase mediated signal transduction
Cellular Component
GO:0005622 intracellular
GO:0005829 cytosol
Protein Structure and Domains
PDB ID
InterPro IPR000198 Rho GTPase-activating protein domain
IPR008936 Rho GTPase activation protein
PFAM PF00620
PRINTS
PIRSF
SMART SM00324
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6P4F7
PhosphoSite PhosphoSite-Q6P4F7
TrEMBL
UniProt Splice Variant
Entrez Gene 9824
UniGene Hs.735394
RefSeq NP_001273409
HUGO HGNC:15783
OMIM 610589
CCDS CCDS66730
HPRD 10656
IMGT
EMBL AC123768 AK303025 AK316437 BC039563 BC063444 D87717
GenPept AAH39563 AAH63444 BAA13442 BAG64151 BAH14808

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca