Version 5.4
Homo sapiens Protein: SLC12A6
Summary
InnateDB Protein IDBP-603278.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC12A6
Protein Name solute carrier family 12 (potassium/chloride transporters), member 6
Synonyms ACCPN; KCC3; KCC3A; KCC3B;
Species Homo sapiens
Ensembl Protein ENSP00000454069
InnateDB Gene IDBG-5416 (SLC12A6)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0015377 cation:chloride symporter activity
GO:0015379 potassium:chloride symporter activity
Biological Process
GO:0006810 transport
GO:0006811 ion transport
GO:0055085 transmembrane transport
GO:1902476 chloride transmembrane transport
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR000076 K-Cl co-transporter
IPR004841 Amino acid permease/ SLC12A domain
IPR004842 Na/K/Cl co-transporter superfamily
PFAM PF00324
PRINTS PR01081
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL H0YNJ5
UniProt Splice Variant
Entrez Gene 9990
UniGene Hs.510939
RefSeq
HUGO HGNC:10914
OMIM 604878
CCDS
HPRD 09220
IMGT
EMBL AC021822 AC079203 CH471125
GenPept EAW92298 EAW92299

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca