Version 5.4
Homo sapiens Protein: MRS2
Summary
InnateDB Protein IDBP-64885.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MRS2
Protein Name MRS2 magnesium homeostasis factor homolog (S. cerevisiae)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000367604
InnateDB Gene IDBG-64879 (MRS2)
Protein Structure
UniProt Annotation
Function Magnesium transporter that may mediate the influx of magnesium into the mitochondrial matrix. {ECO:0000269PubMed:11401429}.
Subcellular Localization Mitochondrion inner membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0015095 magnesium ion transmembrane transporter activity
Biological Process
GO:0015693 magnesium ion transport
Cellular Component
GO:0005743 mitochondrial inner membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9HD23
PhosphoSite PhosphoSite-Q9HD23
TrEMBL
UniProt Splice Variant
Entrez Gene 57380
UniGene Hs.743637
RefSeq NP_001273194
HUGO HGNC:13785
OMIM
CCDS CCDS75408
HPRD 17603
IMGT
EMBL AF288288 AF293076 AF293078 AK054587 AK291058 AK298849 AL359713 BC001028 BC069009 CH471087
GenPept AAG01170 AAH01028 AAH69009 AAK38615 AAK38617 BAF83747 BAG51394 BAG60974 CAI17107 CAI17108 CAI17109 EAW55445 EAW55446

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca