Homo sapiens Protein: DDX3X
Summary
InnateDB Protein IDBP-680423.1
Last Modified 2018-06-05 [Report errors or provide feedback]
Gene Symbol DDX3X
Protein Name DEAD-box helicase 3, X-linked
Synonyms CAP-Rf; DBX; DDX14; DDX3; HLP2; MRX102;
Species Homo sapiens
Ensembl Protein ENSP00000486443
InnateDB Gene IDBG-128290 (DDX3X)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 261 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Experimentally validated
Total 261 [view]
Protein-Protein 255 [view]
Protein-DNA 5 [view]
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0016787 hydrolase activity
Biological Process
Cellular Component
GO:0005634 nucleus
GO:0005829 cytosol
Protein Structure and Domains
PDB ID
InterPro IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site
IPR001650 Helicase, C-terminal
IPR011545 DEAD/DEAH box helicase domain
IPR014001 Helicase superfamily 1/2, ATP-binding domain
IPR014014 RNA helicase, DEAD-box type, Q motif
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF00271
PF00270
PRINTS
PIRSF
SMART SM00490
SM00487
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL A0A0D9SFB3
UniProt Splice Variant
Entrez Gene 1654
UniGene
RefSeq
HUGO HGNC:2745
OMIM 300160
CCDS
HPRD
IMGT
EMBL AL391647 Z93015
GenPept