Version 5.4
Bos taurus Protein: CD3D
Summary
InnateDB Protein IDBP-682792.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CD3D
Protein Name T-cell surface glycoprotein CD3 delta chain
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000008462
InnateDB Gene IDBG-631274 (CD3D)
Protein Structure
UniProt Annotation
Function The CD3 complex mediates signal transduction.
Subcellular Localization Membrane; Single-pass type I membrane protein.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003713 transcription coactivator activity
GO:0004888 transmembrane signaling receptor activity
GO:0005515 protein binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0007166 cell surface receptor signaling pathway
GO:0030217 T cell differentiation
GO:0045059 positive thymic T cell selection
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0042101 T cell receptor complex
GO:0042105 alpha-beta T cell receptor complex
Protein Structure and Domains
PDB ID
InterPro IPR003110 Phosphorylated immunoreceptor signalling ITAM
PFAM PF02189
PRINTS
PIRSF
SMART SM00077
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q28072
PhosphoSite PhosphoSite-
TrEMBL V6F7N3
UniProt Splice Variant
Entrez Gene 281053
UniGene Bt.88072
RefSeq NP_001029205
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC102857 GJ062397 X53269
GenPept AAI02858 CAA37367 DAA22353

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca