InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: S100A16

Summary

InnateDB Protein

IDBP-684490.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

S100A16

Protein Name

Protein S100-A16

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000018877

InnateDB Gene

IDBG-632835 (S100A16)

Protein Structure

UniProt Annotation

Function

Calcium-binding protein. Binds one calcium ion per monomer (By similarity). {ECO:0000250}.

Subcellular Localization

Nucleus, nucleolus {ECO:0000250}. Cytoplasm {ECO:0000250}. Note=Primarily nucleolar. Translocates from the nucleolus to the cytoplasm in response to an increase of intracellular calcium levels (By similarity). {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 27 interaction(s) predicted by orthology.

Predicted by orthology
Total	27 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005509	calcium ion binding
GO:0042803	protein homodimerization activity
GO:0044822	poly(A) RNA binding
GO:0046872	metal ion binding

Biological Process

GO:0051592

response to calcium ion

Cellular Component

GO:0005634	nucleus
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005886	plasma membrane
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR002048 EF-hand domain
IPR013787 S100/CaBP-9k-type, calcium binding, subdomain

PFAM

PF00036
PF13202
PF13405
PF01023

PRINTS

PIRSF

SMART

SM00054

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q0VCM0

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

505679

UniGene

RefSeq

NP_001068686

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC120103

GenPept

AAI20104