Version 5.4
| Bos taurus Protein: AP1M2 | |||||||||||
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| Summary | |||||||||||
| InnateDB Protein | IDBP-695873.2 | ||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
| Gene Symbol | AP1M2 | ||||||||||
| Protein Name | AP-1 complex subunit mu-2 | ||||||||||
| Synonyms | |||||||||||
| Species | Bos taurus | ||||||||||
| Ensembl Protein | ENSBTAP00000043007 | ||||||||||
| InnateDB Gene | IDBG-643319 (AP1M2) | ||||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||||
| Function | Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. {ECO:0000250UniProtKB:Q9Y6Q5, ECO:0000269PubMed:12604586}. | ||||||||||
| Subcellular Localization | Cytoplasmic vesicle, clathrin-coated vesicle membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Golgi apparatus {ECO:0000250}. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex. {ECO:0000250}. | ||||||||||
| Disease Associations | |||||||||||
| Tissue Specificity | |||||||||||
| Comments | |||||||||||
| Interactions | |||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||||
| PDB ID | |||||||||||
| InterPro |
IPR001392
Clathrin adaptor, mu subunit IPR008968 Clathrin adaptor, mu subunit, C-terminal IPR011012 Longin-like domain IPR022775 AP complex, mu/sigma subunit IPR028565 Mu homology domain |
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| PFAM |
PF00928
PF01217 |
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| PRINTS |
PR00314
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| PIRSF |
PIRSF005992
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| SMART | |||||||||||
| TIGRFAMs | |||||||||||
| Post-translational Modifications | |||||||||||
| Modification | |||||||||||
| Cross-References | |||||||||||
| SwissProt | Q3SYW1 | ||||||||||
| PhosphoSite | PhosphoSite- | ||||||||||
| TrEMBL | |||||||||||
| UniProt Splice Variant | |||||||||||
| Entrez Gene | 515766 | ||||||||||
| UniGene | Bt.38351 | ||||||||||
| RefSeq | NP_001029683 | ||||||||||
| HUGO | |||||||||||
| OMIM | |||||||||||
| CCDS | |||||||||||
| HPRD | |||||||||||
| IMGT | |||||||||||
| EMBL | BC103358 | ||||||||||
| GenPept | AAI03359 | ||||||||||