InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: DDX41

Summary

InnateDB Protein

IDBP-697994.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

DDX41

Protein Name

probable ATP-dependent RNA helicase DDX41

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000041074

InnateDB Gene

IDBG-645290 (DDX41)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.

Predicted by orthology
Total	15 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003676	nucleic acid binding
GO:0003677	DNA binding
GO:0004386	helicase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0008270	zinc ion binding
GO:0016787	hydrolase activity
GO:0044822	poly(A) RNA binding

Biological Process

GO:0008152	metabolic process
GO:0035458	cellular response to interferon-beta
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0051607	defense response to virus

Cellular Component

GO:0005634	nucleus
GO:0005783	endoplasmic reticulum
GO:0016020	membrane
GO:0071013	catalytic step 2 spliceosome

Protein Structure and Domains

PDB ID

InterPro

IPR001650 Helicase, C-terminal
IPR001878 Zinc finger, CCHC-type
IPR011545 DEAD/DEAH box helicase domain
IPR014001 Helicase, superfamily 1/2, ATP-binding domain
IPR014014 RNA helicase, DEAD-box type, Q motif
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00271
PF00098
PF00270

PRINTS

PIRSF

SMART

SM00490
SM00343
SM00487

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite