InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: GNAO1

Summary

InnateDB Protein

IDBP-750630.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GNAO1

Protein Name

Synonyms

EIEE17; G-ALPHA-o; GNAO;

Species

Homo sapiens

Ensembl Protein

ENSP00000454971

InnateDB Gene

IDBG-31702 (GNAO1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 22 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.

Experimentally validated
Total	22 [view]
Protein-Protein	22 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	8 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003924	GTPase activity
GO:0004871	signal transducer activity
GO:0005525	GTP binding
GO:0019001	guanyl nucleotide binding
GO:0031683	G-protein beta/gamma-subunit complex binding

Biological Process

GO:0006184	GTP catabolic process
GO:0007186	G-protein coupled receptor signaling pathway
GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR001019 Guanine nucleotide binding protein (G-protein), alpha subunit
IPR001408 G-protein alpha subunit, group I
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00503

PRINTS

PR00318
PR00441

PIRSF

SMART

SM00275

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt