Homo sapiens Protein: IRF3
Summary
InnateDB Protein IDBP-761257.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IRF3
Protein Name
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000470905
InnateDB Gene IDBG-63225 (IRF3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 156 experimentally validated interaction(s) in this database.
They are also associated with 21 interaction(s) predicted by orthology.
Experimentally validated
Total 156 [view]
Protein-Protein 105 [view]
Protein-DNA 51 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 21 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000975 regulatory region DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
Biological Process
GO:0045087 innate immune response (InnateDB)
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR001346 Interferon regulatory factor DNA-binding domain
PFAM PF00605
PRINTS PR00267
PIRSF
SMART SM00348
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q71U93
UniProt Splice Variant
Entrez Gene 3661
UniGene Hs.75254
RefSeq
HUGO HGNC:6118
OMIM 603734
CCDS
HPRD 04769
IMGT
EMBL AC011495 AF112181
GenPept AAD05262