Version 5.4
Homo sapiens Protein: DISC1
Summary
InnateDB Protein IDBP-811947.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DISC1
Protein Name disrupted in schizophrenia 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000473586
InnateDB Gene IDBG-107439 (DISC1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 140 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 140 [view]
Protein-Protein 140 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0000226 microtubule cytoskeleton organization
GO:0001764 neuron migration
GO:0002052 positive regulation of neuroblast proliferation
GO:0030177 positive regulation of Wnt signaling pathway
Cellular Component
GO:0005739 mitochondrion
GO:0005813 centrosome
GO:0005874 microtubule
GO:0014069 postsynaptic density
GO:0030054 cell junction
GO:0045211 postsynaptic membrane
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9NRI5
PhosphoSite PhosphoSite-Q9NRI5
TrEMBL
UniProt Splice Variant
Entrez Gene 27185
UniGene
RefSeq NP_001158027
HUGO HGNC:2888
OMIM 605210
CCDS CCDS59206
HPRD
IMGT
EMBL AB007926 AF222980 AF222983 AF222987 AJ506177 AJ506178 AL136171 AL161743 AL359543 AL445200 AL450284 AL626763 AL751364 FJ804174 FJ804178 FJ804180 FJ804182 FJ804184 FJ804186 FJ804190 FJ804191 FJ804196 FJ804197 FJ804199 FJ804200 FJ804203 FJ804204 FJ804205 FJ804208 FJ804212
GenPept AAF73874 AAF73877 AAF73889 ACR40040 ACR40044 ACR40046 ACR40048 ACR40050 ACR40052 ACR40056 ACR40057 ACR40062 ACR40063 ACR40065 ACR40066 ACR40069 ACR40070 ACR40071 ACR40074 ACR40078 BAA32302 CAD44628 CAD44631 CAH70955 CAH70956 CAH70957 CAI15677 CAI15679 CAI17204 CAI17206 CAI17207 CAI21886 CAI21888 CAI22543 CAI23013

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca