Homo sapiens Gene: LMO4
Summary
InnateDB Gene IDBG-100124.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LMO4
Gene Name LIM domain only 4
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000143013
Encoded Proteins
LIM domain only 4
LIM domain only 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a cysteine-rich protein that contains two LIM domains but lacks a DNA-binding homeodomain. The encoded protein may play a role as a transcriptional regulator or as an oncogene. [provided by RefSeq, Aug 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:87328468-87348923
Strand Forward strand
Band p22.3
Transcripts
ENST00000370544 ENSP00000359575
ENST00000370542 ENSP00000359573
ENST00000495705
ENST00000489303
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 55 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated
Total 55 [view]
Protein-Protein 54 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001158 enhancer sequence-specific DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
Biological Process
GO:0001843 neural tube closure
GO:0003281 ventricular septum development
GO:0006366 transcription from RNA polymerase II promoter
GO:0021514 ventral spinal cord interneuron differentiation
GO:0021522 spinal cord motor neuron differentiation
GO:0021527 spinal cord association neuron differentiation
GO:0031333 negative regulation of protein complex assembly
GO:0042659 regulation of cell fate specification
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0048538 thymus development
GO:0050865 regulation of cell activation
Cellular Component
GO:0005667 transcription factor complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
KEGG
INOH
PID NCI
Validated nuclear estrogen receptor alpha network
SHP2 signaling
IL6-mediated signaling events
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.436792 Hs.593530
RefSeq NM_006769 XM_005271291
HUGO
OMIM
CCDS CCDS713
HPRD 09122
IMGT
EMBL
GenPept
RNA Seq Atlas