Version 5.4
Homo sapiens Gene: PDE4DIP
Summary
InnateDB Gene IDBG-101638.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PDE4DIP
Gene Name phosphodiesterase 4D interacting protein
Synonyms CMYA2; MMGL
Species Homo sapiens
Ensembl Gene ENSG00000178104
Encoded Proteins
IDBP-101644
phosphodiesterase 4D interacting protein
IDBP-101648
phosphodiesterase 4D interacting protein
IDBP-101652
phosphodiesterase 4D interacting protein
IDBP-101654
phosphodiesterase 4D interacting protein
IDBP-101656
phosphodiesterase 4D interacting protein
IDBP-101662
phosphodiesterase 4D interacting protein
IDBP-591261
phosphodiesterase 4D interacting protein
IDBP-593748
phosphodiesterase 4D interacting protein
IDBP-810990
phosphodiesterase 4D interacting protein
IDBP-810925
phosphodiesterase 4D interacting protein
IDBP-589499
phosphodiesterase 4D interacting protein
IDBP-595151
phosphodiesterase 4D interacting protein
IDBP-588214
phosphodiesterase 4D interacting protein
IDBP-595495
phosphodiesterase 4D interacting protein
IDBP-587694
phosphodiesterase 4D interacting protein
IDBP-603669
phosphodiesterase 4D interacting protein
IDBP-810809
phosphodiesterase 4D interacting protein
IDBP-583249
phosphodiesterase 4D interacting protein
IDBP-810927
phosphodiesterase 4D interacting protein
IDBP-810929
phosphodiesterase 4D interacting protein
IDBP-810934
phosphodiesterase 4D interacting protein
IDBP-810938
phosphodiesterase 4D interacting protein
IDBP-810939
phosphodiesterase 4D interacting protein
IDBP-810940
phosphodiesterase 4D interacting protein
IDBP-810942
phosphodiesterase 4D interacting protein
IDBP-810945
phosphodiesterase 4D interacting protein
IDBP-810947
phosphodiesterase 4D interacting protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene serves to anchor phosphodiesterase 4D to the Golgi/centrosome region of the cell. Defects in this gene may be a cause of myeloproliferative disorder (MBD) associated with eosinophilia. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:148808181-149048286
Strand Forward strand
Band q21.2
Transcripts
ENST00000369356 ENSP00000358363
ENST00000369354 ENSP00000358360
ENST00000369351 ENSP00000358357
ENST00000369349 ENSP00000358355
ENST00000313431 ENSP00000316434
ENST00000369347 ENSP00000358353
ENST00000469668
ENST00000460027
ENST00000464924
ENST00000479369
ENST00000481227
ENST00000494734
ENST00000491426 ENSP00000431596
ENST00000467859
ENST00000479408 ENSP00000436791
ENST00000496263
ENST00000477941
ENST00000464103 ENSP00000481731
ENST00000528060
ENST00000525630
ENST00000524974 ENSP00000480806
ENST00000530062 ENSP00000436694
ENST00000526182
ENST00000533768
ENST00000534367
ENST00000530130 ENSP00000432498
ENST00000526664
ENST00000534466
ENST00000527901
ENST00000525886
ENST00000529945 ENSP00000433392
ENST00000533845
ENST00000534536 ENSP00000435920
ENST00000528129 ENSP00000431777
ENST00000526445 ENSP00000435483
ENST00000530472 ENSP00000482121
ENST00000533259 ENSP00000437202
ENST00000620605 ENSP00000479601
ENST00000585156 ENSP00000462316
ENST00000618462 ENSP00000479409
ENST00000617031
ENST00000617527
ENST00000617248
ENST00000610852
ENST00000619981 ENSP00000480590
ENST00000618504 ENSP00000480290
ENST00000617454 ENSP00000484652
ENST00000616206 ENSP00000483081
ENST00000613995 ENSP00000480245
ENST00000621371 ENSP00000483413
ENST00000612094
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 54 experimentally validated interaction(s) in this database.
Experimentally validated
Total 54 [view]
Protein-Protein 52 [view]
Protein-DNA 1 [view]
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005488 binding
GO:0005515 protein binding
GO:0019899 enzyme binding
Biological Process
GO:0043623 cellular protein complex assembly
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005813 centrosome
GO:0030016 myofibril
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000038170
View Gene Order
ENSBTAG00000001564
Not yet available
Cross-References
SwissProt Q5VU43
TrEMBL E9PI71 E9PIN2 E9PJ85 E9PJA9 E9PJK3 E9PJU0 E9PNE0 E9PRJ6 E9PS60 I1VE15
UniProt Splice Variant
Entrez Gene 9659
UniGene Hs.584841 Hs.609003 Hs.617226 Hs.632434 Hs.641529
RefSeq NM_001002810 NM_001002811 NM_001002812 NM_001195260 NM_001195261 NM_001198832 NM_001198834 NM_014644 NM_022359 XM_003846758 XM_005272981 XM_006710059 XM_006710077 XM_006710078 XM_006710079 XM_006710080 XM_006710081 XM_006711653 XM_006711697 XM_006711706 XM_006726349 XM_006726359
HUGO HGNC:15580
OMIM 608117
CCDS CCDS72887 CCDS72888 CCDS72889 CCDS72890 CCDS72891 CCDS72892 CCDS72893 CCDS72894
HPRD
IMGT
EMBL AB007923 AB007946 AB042555 AB042556 AB042557 AB042558 AL138791 AL138796 AL590452 AL831815 AL832024 AL833273 BC004860 BC025406 BC078660 BC110294 BC132717 BC152439 CR749273 DA900724 JQ388960
GenPept AAH04860 AAH25406 AAH78660 AAI10295 AAI32718 AAI52440 AFI41825 BAA32299 BAA32322 BAB17759 BAB17760 BAB17761 BAB17762 CAD38529 CAD89923 CAD91152 CAH18128 CAH72521 CAH72522 CAH72523 CAH72524 CAH72525 CAH72526 CAH72527 CAH72528 CAI22527 CAI22822 CAI22823 CAI22824 CAI22825 CAI22826 CAI22827
RNA Seq Atlas 100996724 100996761 101060254 101929792 101930416 102724173 9659

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca