Homo sapiens Gene: CHD1L
Summary
InnateDB Gene IDBG-101816.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CHD1L
Gene Name chromodomain helicase DNA binding protein 1-like
Synonyms ALC1; CHDL;
Species Homo sapiens
Ensembl Gene ENSG00000131778
Encoded Proteins
chromodomain helicase DNA binding protein 1-like
chromodomain helicase DNA binding protein 1-like
chromodomain helicase DNA binding protein 1-like
chromodomain helicase DNA binding protein 1-like
chromodomain helicase DNA binding protein 1-like
chromodomain helicase DNA binding protein 1-like
chromodomain helicase DNA binding protein 1-like
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a DNA helicase protein involved in DNA repair. The protein converts ATP to add poly(ADP-ribose) as it regulates chromatin relaxation following DNA damage. Several alternatively spliced transcripts variants have been described for this gene. [provided by RefSeq, Jan 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:147242641-147295766
Strand Forward strand
Band q21.1
Transcripts
ENST00000369258 ENSP00000358262
ENST00000369259 ENSP00000358263
ENST00000361293 ENSP00000355100
ENST00000431239 ENSP00000389031
ENST00000467213 ENSP00000477985
ENST00000488864 ENSP00000482764
ENST00000492728
ENST00000485113
ENST00000469625
ENST00000622533 ENSP00000480553
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 39 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 39 [view]
Protein-Protein 38 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0004003 ATP-dependent DNA helicase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0016887 ATPase activity
Biological Process
GO:0006200 ATP catabolic process
GO:0006281 DNA repair
GO:0006338 chromatin remodeling
GO:0006974 cellular response to DNA damage stimulus
GO:0032508 DNA duplex unwinding
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005886 plasma membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.191164 Hs.609756
RefSeq NM_001256336 NM_001256337 NM_001256338 NM_004284 NM_024568 XM_006711636 XM_006711639
HUGO
OMIM
CCDS CCDS58021 CCDS58022 CCDS72882 CCDS927
HPRD 09880
IMGT
EMBL
GenPept
RNA Seq Atlas