Version 5.4
Homo sapiens Gene: PHLDA3
Summary
InnateDB Gene IDBG-105766.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PHLDA3
Gene Name pleckstrin homology-like domain, family A, member 3
Synonyms TIH1
Species Homo sapiens
Ensembl Gene ENSG00000174307
Encoded Proteins
IDBP-105768
pleckstrin homology-like domain, family A, member 3
IDBP-105770
pleckstrin homology-like domain, family A, member 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 1:201464383-201469237
Strand Reverse strand
Band q32.1
Transcripts
ENST00000367311 ENSP00000356280
ENST00000367309 ENSP00000356278
ENST00000485436
ENST00000497057
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 26 experimentally validated interaction(s) in this database.
Experimentally validated
Total 26 [view]
Protein-Protein 26 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005546 phosphatidylinositol-4,5-bisphosphate binding
GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding
GO:0010314 phosphatidylinositol-5-phosphate binding
GO:0032266 phosphatidylinositol-3-phosphate binding
GO:0043325 phosphatidylinositol-3,4-bisphosphate binding
GO:0080025 phosphatidylinositol-3,5-bisphosphate binding
Biological Process
GO:0009653 anatomical structure morphogenesis
GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0043065 positive regulation of apoptotic process
GO:0051898 negative regulation of protein kinase B signaling
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Gene ID
Gene Order
ENSMUSG00000041801
View Gene Order
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_012396
HUGO
OMIM
CCDS CCDS1412
HPRD 09519
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca