Version 5.4
Homo sapiens Gene: TRAF3IP3
Summary
InnateDB Gene IDBG-106436.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TRAF3IP3
Gene Name TRAF3 interacting protein 3
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000009790
Encoded Proteins
IDBP-106440
TRAF3 interacting protein 3
IDBP-106442
TRAF3 interacting protein 3
IDBP-106444
TRAF3 interacting protein 3
IDBP-106448
TRAF3 interacting protein 3
IDBP-226985
TRAF3 interacting protein 3
IDBP-482193
TRAF3 interacting protein 3
IDBP-473435
TRAF3 interacting protein 3
IDBP-476288
TRAF3 interacting protein 3
IDBP-482538
TRAF3 interacting protein 3
IDBP-594581
TRAF3 interacting protein 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The gene encodes a protein that mediates cell growth by modulating the c-Jun N-terminal kinase signal transduction pathway. The encoded protein may also interact with a large multiprotein assembly containing the phosphatase 2A catalytic subunit. [provided by RefSeq, May 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:209756032-209782320
Strand Forward strand
Band q32.2
Transcripts
ENST00000367025 ENSP00000355992
ENST00000367026 ENSP00000355993
ENST00000367024 ENSP00000355991
ENST00000367023 ENSP00000355990
ENST00000400959 ENSP00000383743
ENST00000478359 ENSP00000417665
ENST00000468672
ENST00000479796 ENSP00000419180
ENST00000476050
ENST00000487271 ENSP00000418906
ENST00000474496
ENST00000477431 ENSP00000417417
ENST00000488702
ENST00000471368 ENSP00000436982
ENST00000460314
ENST00000467830
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 21 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 21 [view]
Protein-Protein 21 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000037318
View Gene Order
ENSBTAG00000002846
Not yet available
Cross-References
SwissProt Q9Y228
TrEMBL B1AJU2 C9J0C0 C9JBA0 C9JXB3 E2QRE5 H0YF09
UniProt Splice Variant
Entrez Gene 80342
UniGene Hs.147434 Hs.608357 Hs.634602
RefSeq NM_001287754 NM_025228
HUGO HGNC:30766
OMIM 608255
CCDS CCDS1490 CCDS73023
HPRD
IMGT
EMBL AL022398 AL049667 BC110302 BC130417 BC144139 CH471100
GenPept AAI10303 AAI30418 AAI44140 CAB41242 CAI95687 EAW93444
RNA Seq Atlas 80342

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca