Version 5.4
Homo sapiens Gene: NCAPG
Summary
InnateDB Gene IDBG-11146.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NCAPG
Gene Name non-SMC condensin I complex, subunit G
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000109805
Encoded Proteins
IDBP-11148
non-SMC condensin I complex, subunit G
IDBP-478321
non-SMC condensin I complex, subunit G
IDBP-482862
non-SMC condensin I complex, subunit G
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a subunit of the condensin complex, which is responsible for the condensation and stabilization of chromosomes during mitosis and meiosis. Phosphorylation of the encoded protein activates the condensin complex. There are pseudogenes for this gene on chromosomes 8 and 15. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:17810902-17844862
Strand Forward strand
Band p15.31
Transcripts
ENST00000251496 ENSP00000251496
ENST00000514176 ENSP00000423042
ENST00000513226
ENST00000509719
ENST00000510063 ENSP00000425625
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 39 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 39 [view]
Protein-Protein 31 [view]
Protein-DNA 8 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005488 binding
GO:0005515 protein binding
Biological Process
GO:0000278 mitotic cell cycle
GO:0007076 mitotic chromosome condensation
Cellular Component
GO:0000793 condensed chromosome
GO:0000796 condensin complex
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005829 cytosol
GO:0015629 actin cytoskeleton
GO:0016020 membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000015880
View Gene Order
ENSBTAG00000021582
Not yet available
Pathways
NETPATH
REACTOME
REACT_150260
Condensation of Prometaphase Chromosomes pathway
REACT_682
Mitotic Prometaphase pathway
REACT_115566
Cell Cycle pathway
REACT_910
M Phase pathway
REACT_152
Cell Cycle, Mitotic pathway
KEGG
INOH
PID NCI
aurora_b_pathway
Aurora B signaling
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.567567
RefSeq NM_022346 XM_006713971
HUGO
OMIM
CCDS CCDS3424
HPRD 12097
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca