Mus musculus Gene: Nup155
Summary
InnateDB Gene IDBG-128404.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nup155
Gene Name nucleoporin 155
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000022142
Encoded Proteins
nucleoporin 155
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000113569:
Nucleoporins are the main components of the nuclear pore complex (NPC) of eukaryotic cells. They are involved in the bidirectional trafficking of molecules, especially mRNAs and proteins, between the nucleus and the cytoplasm. The protein encoded by this gene does not contain the typical FG repeat sequences found in most vertebrate nucleoporins. Two protein isoforms are encoded by transcript variants of this gene. [provided by RefSeq, Jul 2008]
Nucleoporins are proteins that play an important role in the assembly and functioning of the nuclear pore complex (NPC) which regulates the movement of macromolecules across the nuclear envelope (NE). The protein encoded by this gene plays a role in the fusion of NE vesicles and formation of the double membrane NE. The protein may also be involved in cardiac physiology and may be associated with the pathogenesis of atrial fibrillation. Alternative splicing results in multiple transcript variants of this gene. A pseudogene associated with this gene is located on chromosome 6. [provided by RefSeq, May 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:8109313-8159857
Strand Forward strand
Band A1
Transcripts
ENSMUST00000163765 ENSMUSP00000128819
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 23 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 23 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0017056 structural constituent of nuclear pore
Biological Process
GO:0006406 mRNA export from nucleus
GO:0006606 protein import into nucleus
GO:0006998 nuclear envelope organization
GO:0086014 atrial cardiac muscle cell action potential
Cellular Component
GO:0005635 nuclear envelope
GO:0005643 nuclear pore
GO:0016020 membrane
GO:0031965 nuclear membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Nuclear Envelope Breakdown pathway
Cell Cycle, Mitotic pathway
Disease pathway
Nuclear Pore Complex (NPC) Disassembly pathway
SLC-mediated transmembrane transport pathway
Regulation of Glucokinase by Glucokinase Regulatory Protein pathway
Cell Cycle pathway
Metabolism pathway
M Phase pathway
Transcriptional regulation by small RNAs pathway
Glucose transport pathway
Transmembrane transport of small molecules pathway
Hexose transport pathway
Glycogen storage diseases pathway
Gene Expression pathway
Regulatory RNA pathways pathway
Mitotic Prophase pathway
Myoclonic epilepsy of Lafora pathway
Metabolism of carbohydrates pathway
KEGG
RNA transport pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
ISG15 antiviral mechanism pathway
Regulation of Glucokinase by Glucokinase Regulatory Protein pathway
Glucose transport pathway
Hexose transport pathway
Nuclear import of Rev protein pathway
Vpr-mediated nuclear import of PICs pathway
Rev-mediated nuclear export of HIV RNA pathway
Viral Messenger RNA Synthesis pathway
Late Phase of HIV Life Cycle pathway
Transmembrane transport of small molecules pathway
Influenza Infection pathway
Interactions of Vpr with host cellular proteins pathway
Myoclonic epilepsy of Lafora pathway
Antiviral mechanism by IFN-stimulated genes pathway
Cytokine Signaling in Immune system pathway
Metabolism of carbohydrates pathway
Transcriptional regulation by small RNAs pathway
Nuclear Pore Complex (NPC) Disassembly pathway
Influenza Viral RNA Transcription and Replication pathway
Interferon Signaling pathway
Cell Cycle pathway
Immune System pathway
M Phase pathway
HIV Life Cycle pathway
Mitotic Prophase pathway
Cell Cycle, Mitotic pathway
HIV Infection pathway
Influenza Life Cycle pathway
Metabolism pathway
Host Interactions of HIV factors pathway
SLC-mediated transmembrane transport pathway
Interactions of Rev with host cellular proteins pathway
Gene Expression pathway
Nuclear Envelope Breakdown pathway
Disease pathway
Glycogen storage diseases pathway
Regulatory RNA pathways pathway
KEGG
RNA transport pathway
INOH
PID NCI
Cross-References
SwissProt Q99P88
TrEMBL Q3USP6 Q6ZQ45 Q8BKJ0 Q8BLF5 Q8BUA6
UniProt Splice Variant
Entrez Gene 170762
UniGene Mm.295168 Mm.406046 Mm.415720
RefSeq NM_133227 XM_006519972
OMIM
CCDS CCDS37034
HPRD
IMGT
MGI ID MGI:2181182
MGI Symbol Nup155
EMBL AF322375 AK045334 AK051801 AK086426 AK129217 AK140214
GenPept AAK11317 BAC32314 BAC34774 BAC39665 BAC98027 BAE24285
RNA Seq Atlas 170762