Version 5.4
Mus musculus Gene: Esco1
Summary
InnateDB Gene IDBG-128455.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Esco1
Gene Name establishment of cohesion 1 homolog 1 (S. cerevisiae)
Synonyms A930014I12Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000024293
Encoded Proteins
IDBP-128457
establishment of cohesion 1 homolog 1 (S. cerevisiae)
IDBP-128459
establishment of cohesion 1 homolog 1 (S. cerevisiae)
IDBP-248707
establishment of cohesion 1 homolog 1 (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000141446:
ESCO1 belongs to a conserved family of acetyltransferases involved in sister chromatid cohesion (Hou and Zou, 2005 [PubMed 15958495]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:10566602-10610352
Strand Reverse strand
Band A1
Transcripts
ENSMUST00000025142 ENSMUSP00000025142
ENSMUST00000097670 ENSMUSP00000095274
ENSMUST00000115864 ENSMUSP00000111530
ENSMUST00000127099
ENSMUST00000145320
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0016746 transferase activity, transferring acyl groups
GO:0046872 metal ion binding
Biological Process
GO:0006275 regulation of DNA replication
GO:0007062 sister chromatid cohesion
GO:0034421 post-translational protein acetylation
Cellular Component
GO:0000785 chromatin
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000141446
View Gene Order
ENSBTAG00000017597
Not yet available
Pathways
NETPATH
REACTOME
REACT_249770
Cell Cycle, Mitotic pathway
REACT_188804
Cell Cycle pathway
REACT_196614
Establishment of Sister Chromatid Cohesion pathway
REACT_253623
S Phase pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_150266
Establishment of Sister Chromatid Cohesion pathway
REACT_899
S Phase pathway
REACT_115566
Cell Cycle pathway
REACT_152
Cell Cycle, Mitotic pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q69Z69
TrEMBL
UniProt Splice Variant
Entrez Gene 77805
UniGene Mm.210996 Mm.413023 Mm.468860
RefSeq NM_001081222 XM_006526353
OMIM
CCDS CCDS37737
HPRD
IMGT
MGI ID MGI:1925055
MGI Symbol Esco1
EMBL AC102441 AK045656 AK049589 AK173297 BC008220 BC151069 BC151077
GenPept AAH08220 AAI51070 AAI51078 BAC32447 BAC33830 BAD32575
RNA Seq Atlas 77805

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca