Version 5.4
Mus musculus Gene: Coro1b
Summary
InnateDB Gene IDBG-129050.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Coro1b
Gene Name coronin, actin binding protein 1B
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000024835
Encoded Proteins
IDBP-129052
coronin, actin binding protein 1B
IDBP-533942
coronin, actin binding protein 1B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000172725:
Members of the coronin family, such as CORO1B, are WD repeat-containing actin-binding proteins that regulate cell motility (Cai et al., 2005 [PubMed 16027158]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:4148619-4154035
Strand Forward strand
Band A
Transcripts
ENSMUST00000008893 ENSMUSP00000008893
ENSMUST00000123874 ENSMUSP00000118450
ENSMUST00000142878
ENSMUST00000148733
ENSMUST00000134194
ENSMUST00000143613
ENSMUST00000140419
ENSMUST00000135498
ENSMUST00000148189
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 14 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0042802 identical protein binding
GO:0051015 actin filament binding
GO:0071933 Arp2/3 complex binding
Biological Process
GO:0016477 cell migration
GO:0030036 actin cytoskeleton organization
GO:0031529 ruffle organization
GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation
GO:0035767 endothelial cell chemotaxis
GO:0042060 wound healing
GO:0051017 actin filament bundle assembly
GO:0090135 actin filament branching
GO:1902463 protein localization to cell leading edge
GO:2000394 positive regulation of lamellipodium morphogenesis
Cellular Component
GO:0001725 stress fiber
GO:0005737 cytoplasm
GO:0005884 actin filament
GO:0015629 actin cytoskeleton
GO:0030027 lamellipodium
GO:0031252 cell leading edge
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000172725
View Gene Order
ENSBTAG00000004783
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.276859 Mm.471743
RefSeq NM_011778 XM_006531741 XM_006531742 XM_006544896 XM_006544897
OMIM
CCDS CCDS29418
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca