Version 5.4
| Mus musculus Gene: Rad1 | |||||||||||||
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| Summary | |||||||||||||
| InnateDB Gene | IDBG-129395.6 | ||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||
| Gene Symbol | Rad1 | ||||||||||||
| Gene Name | RAD1 homolog (S. pombe) | ||||||||||||
| Synonyms | mRAD1 | ||||||||||||
| Species | Mus musculus | ||||||||||||
| Ensembl Gene | ENSMUSG00000022248 | ||||||||||||
| Encoded Proteins |
RAD1 homolog (S. pombe)
RAD1 homolog (S. pombe)
RAD1 homolog (S. pombe)
RAD1 homolog (S. pombe)
RAD1 homolog (S. pombe)
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||
| Entrez Gene | |||||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000113456:
This gene encodes a component of a heterotrimeric cell cycle checkpoint complex, known as the 9-1-1 complex, that is activated to stop cell cycle progression in response to DNA damage or incomplete DNA replication. The 9-1-1 complex is recruited by RAD17 to affected sites where it may attract specialized DNA polymerases and other DNA repair effectors. Alternatively spliced transcript variants of this gene have been described. [provided by RefSeq, Jan 2009] |
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| Gene Information | |||||||||||||
| Type | Protein coding | ||||||||||||
| Genomic Location | Chromosome 15:10486018-10499063 | ||||||||||||
| Strand | Forward strand | ||||||||||||
| Band | A1 | ||||||||||||
| Transcripts | |||||||||||||
| Interactions | |||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||||||
| NETPATH | |||||||||||||
| REACTOME |
Cell Cycle pathway
Cell Cycle Checkpoints pathway
G2/M Checkpoints pathway
Activation of ATR in response to replication stress pathway
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| KEGG | |||||||||||||
| INOH | |||||||||||||
| PID NCI | |||||||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||||||
| NETPATH | |||||||||||||
| REACTOME |
Activation of ATR in response to replication stress pathway
G2/M Checkpoints pathway
Cell Cycle pathway
Cell Cycle Checkpoints pathway
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| KEGG | |||||||||||||
| INOH | |||||||||||||
| PID NCI |
Fanconi anemia pathway
ATR signaling pathway
Regulation of Telomerase
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| Cross-References | |||||||||||||
| SwissProt | Q9QWZ1 | ||||||||||||
| TrEMBL | E9PXK0 E9PY19 F7CJR1 | ||||||||||||
| UniProt Splice Variant | |||||||||||||
| Entrez Gene | 19355 | ||||||||||||
| UniGene | Mm.38376 | ||||||||||||
| RefSeq | NM_001289447 NM_001289448 NM_011232 XM_006520039 XM_006520040 | ||||||||||||
| OMIM | |||||||||||||
| CCDS | CCDS27379 CCDS70618 | ||||||||||||
| HPRD | |||||||||||||
| IMGT | |||||||||||||
| MGI ID | MGI:1316678 | ||||||||||||
| MGI Symbol | Rad1 | ||||||||||||
| EMBL | AC102101 AF038841 AF058394 AF073523 AF074718 AF076842 AF084514 AJ004976 AK146533 AK148098 AK150466 AK168588 BC048693 | ||||||||||||
| GenPept | AAC14139 AAC27248 AAC35551 AAC95465 AAC95524 AAC98094 AAH48693 BAE27240 BAE28343 BAE29583 BAE40457 CAA06250 | ||||||||||||
| RNA Seq Atlas | 19355 | ||||||||||||