Version 5.4
Mus musculus Gene: Nid1
Summary
InnateDB Gene IDBG-130600.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nid1
Gene Name nidogen 1
Synonyms A630025O17; entactin; entactin-1; Nid; nidogen-1
Species Mus musculus
Ensembl Gene ENSMUSG00000005397
Encoded Proteins
IDBP-130602
nidogen 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000116962:
This gene encodes a member of the nidogen family of basement membrane glycoproteins. The protein interacts with several other components of basement membranes, and may play a role in cell interactions with the extracellular matrix. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:13437602-13512275
Strand Forward strand
Band A1
Transcripts
ENSMUST00000005532 ENSMUSP00000005532
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 22 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Experimentally validated
Total 22 [view]
Protein-Protein 21 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005518 collagen binding
GO:0043236 laminin binding
GO:0043237 laminin-1 binding
GO:0043394 proteoglycan binding
GO:0050840 extracellular matrix binding
Biological Process
GO:0007160 cell-matrix adhesion
GO:0008150 biological_process
GO:0010811 positive regulation of cell-substrate adhesion
GO:0030198 extracellular matrix organization
GO:0032836 glomerular basement membrane development
Cellular Component
GO:0005575 cellular_component
GO:0005576 extracellular region
GO:0005578 proteinaceous extracellular matrix
GO:0005604 basement membrane
GO:0005605 basal lamina
GO:0031012 extracellular matrix
GO:0070062 extracellular vesicular exosome
GO:0071944 cell periphery
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000116962
View Gene Order
ENSBTAG00000007244
Not yet available
Pathways
NETPATH
REACTOME
REACT_206066
Extracellular matrix organization pathway
REACT_202342
Laminin interactions pathway
REACT_199052
Degradation of the extracellular matrix pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_118779
Extracellular matrix organization pathway
REACT_118572
Degradation of the extracellular matrix pathway
REACT_169262
Laminin interactions pathway
KEGG
INOH
PID NCI
integrin1_pathway
Beta1 integrin cell surface interactions
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.4691
RefSeq NM_010917
OMIM
CCDS CCDS26244
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca