Version 5.4
Mus musculus Gene: Gng4
Summary
InnateDB Gene IDBG-131055.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gng4
Gene Name guanine nucleotide binding protein (G protein), gamma 4
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000021303
Encoded Proteins
IDBP-131057
guanine nucleotide binding protein (G protein), gamma 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000168243:
Gene Information
Type Protein coding
Genomic Location Chromosome 13:13784059-13827897
Strand Forward strand
Band A1
Transcripts
ENSMUST00000021734 ENSMUSP00000021734
ENSMUST00000138783
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003924 GTPase activity
GO:0004871 signal transducer activity
GO:0005515 protein binding
Biological Process
GO:0006184 GTP catabolic process
GO:0007186 G-protein coupled receptor signaling pathway
GO:0030308 negative regulation of cell growth
Cellular Component
GO:0005834 heterotrimeric G-protein complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000168243
View Gene Order
ENSBTAG00000002908
Not yet available
Pathways
NETPATH
REACTOME
REACT_214393
Inwardly rectifying K+ channels pathway
REACT_231304
Glucagon-type ligand receptors pathway
REACT_254215
Signaling by GPCR pathway
REACT_210399
Glucagon signaling in metabolic regulation pathway
REACT_250061
Class B/2 (Secretin family receptors) pathway
REACT_217323
Integration of energy metabolism pathway
REACT_208267
G protein gated Potassium channels pathway
REACT_203664
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell pathway
REACT_188937
Metabolism pathway
REACT_207065
Activation of GABAB receptors pathway
REACT_226335
Aquaporin-mediated transport pathway
REACT_263148
Regulation of insulin secretion pathway
REACT_213947
Vasopressin regulates renal water homeostasis via Aquaporins pathway
REACT_202800
Potassium Channels pathway
REACT_217868
GABA B receptor activation pathway
REACT_231468
GPCR ligand binding pathway
REACT_253400
Transmembrane transport of small molecules pathway
REACT_224131
GABA receptor activation pathway
REACT_259290
Neuronal System pathway
REACT_188257
Signal Transduction pathway
REACT_226457
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits pathway
REACT_233318
Transmission across Chemical Synapses pathway
REACT_208837
Activation of G protein gated Potassium channels pathway
REACT_248547
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion pathway
REACT_250590
Adrenaline,noradrenaline inhibits insulin secretion pathway
KEGG
mmu04062
Chemokine signaling pathway pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_23946
Prostacyclin signalling through prostacyclin receptor pathway
REACT_23876
Platelet homeostasis pathway
REACT_20653
ADP signalling through P2Y purinoceptor 12 pathway
REACT_19140
ADP signalling through P2Y purinoceptor 1 pathway
REACT_20647
Thromboxane signalling through TP receptor pathway
REACT_21384
Thrombin signalling through proteinase activated receptors (PARs) pathway
REACT_24023
Vasopressin regulates renal water homeostasis via Aquaporins pathway
REACT_18283
G alpha (q) signalling events pathway
REACT_120966
Gastrin-CREB signalling pathway via PKC and MAPK pathway
REACT_19231
G alpha (i) signalling events pathway
REACT_19290
G beta:gamma signalling through PI3Kgamma pathway
REACT_19145
G beta:gamma signalling through PLC beta pathway
REACT_18407
G alpha (12/13) signalling events pathway
REACT_19327
G alpha (s) signalling events pathway
REACT_19333
G alpha (z) signalling events pathway
REACT_18377
Glucagon-type ligand receptors pathway
REACT_18372
Class B/2 (Secretin family receptors) pathway
REACT_15457
G-protein activation pathway
REACT_15295
Opioid Signalling pathway
REACT_25004
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits pathway
REACT_25031
GABA B receptor activation pathway
REACT_21254
Presynaptic function of Kainate receptors pathway
REACT_75831
Activation of G protein gated Potassium channels pathway
REACT_18274
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion pathway
REACT_18339
Adrenaline,noradrenaline inhibits insulin secretion pathway
REACT_18325
Regulation of insulin secretion pathway
REACT_1665
Glucagon signaling in metabolic regulation pathway
REACT_1505
Integration of energy metabolism pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_172761
Ca2+ pathway pathway
REACT_172694
beta-catenin independent WNT signaling pathway
REACT_11045
Signaling by Wnt pathway
REACT_13685
Neuronal System pathway
REACT_14797
Signaling by GPCR pathway
REACT_25199
GABA receptor activation pathway
REACT_75780
G protein gated Potassium channels pathway
REACT_798
Platelet activation, signaling and aggregation pathway
REACT_19388
G-protein beta:gamma signalling pathway
REACT_25330
Activation of GABAB receptors pathway
REACT_111102
Signal Transduction pathway
REACT_19184
GPCR downstream signaling pathway
REACT_75918
Inwardly rectifying K+ channels pathway
REACT_21312
Activation of Kainate Receptors upon glutamate binding pathway
REACT_75908
Potassium Channels pathway
REACT_13477
Transmission across Chemical Synapses pathway
REACT_21340
GPCR ligand binding pathway
REACT_15370
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell pathway
REACT_111217
Metabolism pathway
REACT_20524
Signal amplification pathway
REACT_23887
Aquaporin-mediated transport pathway
REACT_604
Hemostasis pathway
KEGG
hsa04062
Chemokine signaling pathway pathway
INOH
PID NCI
Cross-References
SwissProt P50153
TrEMBL
UniProt Splice Variant
Entrez Gene 14706
UniGene Mm.215394
RefSeq NM_010317 XM_006516555
OMIM
CCDS CCDS36598
HPRD
IMGT
MGI ID MGI:102703
MGI Symbol Gng4
EMBL AF038593 AF038594 BC016506 U37527
GenPept AAB93460 AAC40090 AAH16506
RNA Seq Atlas 14706

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca