Mus musculus Gene: Rgs20
Summary
InnateDB Gene IDBG-131720.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rgs20
Gene Name regulator of G-protein signaling 20
Synonyms 2900073E09Rik; Rgsz1
Species Mus musculus
Ensembl Gene ENSMUSG00000002459
Encoded Proteins
regulator of G-protein signaling 20
regulator of G-protein signaling 20
regulator of G-protein signaling 20
regulator of G-protein signaling 20
regulator of G-protein signaling 20
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000147509:
The protein encoded by this gene belongs to the family of regulator of G protein signaling (RGS) proteins, which are regulatory and structural components of G protein-coupled receptor complexes. RGS proteins inhibit signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound forms. This protein selectively binds to G(z)-alpha and G(alpha)-i2 subunits, and regulates their signaling activities. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:4909576-5070285
Strand Reverse strand
Band A1
Transcripts
ENSMUST00000002533 ENSMUSP00000002533
ENSMUST00000118000 ENSMUSP00000113398
ENSMUST00000119256 ENSMUSP00000113324
ENSMUST00000147158 ENSMUSP00000117380
ENSMUST00000156289
ENSMUST00000133521
ENSMUST00000170566 ENSMUSP00000131165
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 20 interaction(s) predicted by orthology.
Predicted by orthology
Total 20 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005096 GTPase activator activity
GO:0005515 protein binding
Biological Process
GO:0007186 G-protein coupled receptor signaling pathway
GO:0038032 termination of G-protein coupled receptor signaling pathway
GO:0043547 positive regulation of GTPase activity
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
GPCR downstream signaling pathway
Signaling by GPCR pathway
G alpha (z) signalling events pathway
G alpha (i) signalling events pathway
Signal Transduction pathway
KEGG
INOH
GPCR signaling pathway
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
G alpha (i) signalling events pathway
G alpha (z) signalling events pathway
Signaling by GPCR pathway
Signal Transduction pathway
GPCR downstream signaling pathway
Signaling by GPCR pathway
G alpha (i) signalling events pathway
Signal Transduction pathway
GPCR downstream signaling pathway
G alpha (z) signalling events pathway
KEGG
INOH
GPCR signaling pathway
PID NCI
Cross-References
SwissProt Q9QZB1
TrEMBL Q8C5J7
UniProt Splice Variant
Entrez Gene 58175
UniGene Mm.103771
RefSeq NM_021374 XM_006495554 NM_001177795 NM_001290372 XM_006495552
OMIM
CCDS CCDS14807 CCDS48213 CCDS69859
HPRD
IMGT
MGI ID MGI:1929866
MGI Symbol Rgs20
EMBL AC102242 AC102311 AC157807 AF191552 AF191554 AK013773 AK078208 AK158864 BC116925 BC116929
GenPept AAF05756 AAF05757 AAI16926 AAI16930 BAB28987 BAC37173 BAE34700
RNA Seq Atlas 58175