Version 5.4
Mus musculus Gene: Vps41
Summary
InnateDB Gene IDBG-132226.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Vps41
Gene Name vacuolar protein sorting 41 (yeast)
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000041236
Encoded Proteins
IDBP-132228
vacuolar protein sorting 41 (yeast)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000006715:
Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human ortholog of yeast Vps41 protein which is also conserved in Drosophila, tomato, and Arabidopsis. Expression studies in yeast and human indicate that this protein may be involved in the formation and fusion of transport vesicles from the Golgi. Several transcript variants encoding different isoforms have been described for this gene, however, the full-length nature of not all is known. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:18717292-18866809
Strand Forward strand
Band A2
Transcripts
ENSMUST00000072961 ENSMUSP00000072729
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 19 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005488 binding
GO:0005515 protein binding
GO:0008017 microtubule binding
GO:0008270 zinc ion binding
Biological Process
GO:0006886 intracellular protein transport
GO:0016192 vesicle-mediated transport
GO:0048193 Golgi vesicle transport
Cellular Component
GO:0005765 lysosomal membrane
GO:0005769 early endosome
GO:0005770 late endosome
GO:0005798 Golgi-associated vesicle
GO:0005829 cytosol
GO:0015630 microtubule cytoskeleton
GO:0016020 membrane
GO:0030897 HOPS complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000006715
View Gene Order
ENSBTAG00000007305
Not yet available
Cross-References
SwissProt Q5KU39
TrEMBL Q3TS83 Q6PES1
UniProt Splice Variant
Entrez Gene 218035
UniGene Mm.27389 Mm.413098
RefSeq NM_172120
OMIM
CCDS CCDS26257
HPRD
IMGT
MGI ID MGI:1929215
MGI Symbol Vps41
EMBL AB028843 AF327407 AK051658 AK162208 AK164177 BC023243 BC049916 BC057905 BC119362 BC125299
GenPept AAH23243 AAH49916 AAH57905 AAI19363 AAI25300 AAN73032 BAC34707 BAD88410 BAE36792 BAE37664
RNA Seq Atlas 218035

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca