Version 5.4
Mus musculus Gene: Slc4a7
Summary
InnateDB Gene IDBG-132902.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slc4a7
Gene Name solute carrier family 4, sodium bicarbonate cotransporter, member 7
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000021733
Encoded Proteins
IDBP-132904
solute carrier family 4, sodium bicarbonate cotransporter, member 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000033867:
This locus encodes a sodium bicarbonate cotransporter. The encoded transmembrane protein appears to transport sodium and bicarbonate ions in a 1:1 ratio, and is thus considered an electroneutral cotransporter. The encoded protein likely plays a critical role in regulation of intracellular pH involved in visual and auditory sensory transmission. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Apr 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:14703025-14799943
Strand Forward strand
Band A1
Transcripts
ENSMUST00000057015 ENSMUSP00000058313
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005215 transporter activity
GO:0005452 inorganic anion exchanger activity
GO:0008509 anion transmembrane transporter activity
Biological Process
GO:0006810 transport
GO:0006820 anion transport
GO:0021747 cochlear nucleus development
GO:0046666 retinal cell programmed cell death
GO:0060117 auditory receptor cell development
GO:0061299 retina vasculature morphogenesis in camera-type eye
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016324 apical plasma membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000033867
View Gene Order
ENSBTAG00000018227
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_19298
Bicarbonate transporters pathway
REACT_19397
Transport of inorganic cations/anions and amino acids/oligopeptides pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_19118
SLC-mediated transmembrane transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL D3Y272 F8VQC9 Q8BWZ4 U3RKD2
UniProt Splice Variant
Entrez Gene 218756
UniGene Mm.258893 Mm.408322 Mm.472243
RefSeq NM_001033270
OMIM
CCDS CCDS36810
HPRD
IMGT
MGI ID MGI:2443878
MGI Symbol Slc4a7
EMBL AC129580 AK049322 CT025538 GU386352 JQ073566 KF279520
GenPept ADC92004 AEY79769 AGX13876 BAC33682
RNA Seq Atlas 218756

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca