Version 5.4
Mus musculus Gene: Sephs1
Summary
InnateDB Gene IDBG-133926.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sephs1
Gene Name selenophosphate synthetase 1
Synonyms 1110046B24Rik; AA589574; AI505014; AW111620; SELD; SPS; SPS1
Species Mus musculus
Ensembl Gene ENSMUSG00000026662
Encoded Proteins
IDBP-133928
selenophosphate synthetase 1
IDBP-250571
selenophosphate synthetase 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000086475:
This gene encodes an enzyme that synthesizes selenophosphate from selenide and ATP. Selenophosphate is the selenium donor used to synthesize selenocysteine, which is co-translationally incorporated into selenoproteins at in-frame UGA codons. [provided by RefSeq, Sep 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:4881564-4910557
Strand Forward strand
Band A1
Transcripts
ENSMUST00000027973 ENSMUSP00000027973
ENSMUST00000115019 ENSMUSP00000110671
ENSMUST00000144565
ENSMUST00000140045
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 21 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 21 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004756 selenide, water dikinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0042803 protein homodimerization activity
GO:0046982 protein heterodimerization activity
Biological Process
GO:0008150 biological_process
GO:0016310 phosphorylation
Cellular Component
GO:0005886 plasma membrane
GO:0031965 nuclear membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000086475
View Gene Order
ENSBTAG00000008821
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu00450
Selenocompound metabolism pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa00450
Selenocompound metabolism pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.34329
RefSeq NM_175400 XM_006497309
OMIM
CCDS CCDS15659
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca