InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Wdr36

Summary

InnateDB Gene

IDBG-134043.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Wdr36

Gene Name

WD repeat domain 36

Synonyms

Species

Mus musculus

Ensembl Gene

ENSMUSG00000038299

Encoded Proteins

IDBP-134045

WD repeat domain 36

IDBP-621743

WD repeat domain 36

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000134987:
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Mutations in this gene have been associated with adult-onset primary open-angle glaucoma (POAG). [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 18:32837225-32866420

Strand

Forward strand

Band

Transcripts

ENSMUST00000053663	ENSMUSP00000052465
ENSMUST00000166214	ENSMUSP00000132189

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	16 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0001895	retina homeostasis
GO:0006364	rRNA processing
GO:0030516	regulation of axon extension

Cellular Component

GO:0005575	cellular_component
GO:0032040	small-subunit processome

Orthologs

Species

Homo sapiens

Bos taurus

Gene ID

Gene Order

ENSG00000134987

View Gene Order

ENSBTAG00000005489

Not yet available

Pathway Predictions based on Human Orthology Data

NETPATH

NetPath_24

TSLP pathway

REACTOME

KEGG

INOH

PID NCI

Cross-References

SwissProt

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

Mm.38816 Mm.427516 Mm.488763

RefSeq

NM_001110015 NM_001110016 XM_006525847

OMIM

CCDS

CCDS50245 CCDS50246

HPRD

IMGT

MGI ID

MGI Symbol

EMBL

GenPept

RNA Seq Atlas