Version 5.4
Mus musculus Gene: Tram1
Summary
InnateDB Gene IDBG-134285.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tram1
Gene Name translocating chain-associating membrane protein 1
Synonyms 1810049E02Rik; TRAMP
Species Mus musculus
Ensembl Gene ENSMUSG00000025935
Encoded Proteins
IDBP-134287
translocating chain-associating membrane protein 1
IDBP-788820
translocating chain-associating membrane protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000067167:
This gene encodes a multi-pass membrane protein that is part of the mammalian endoplasmic reticulum. The encoded protein influences glycosylation and facilitates the translocation of secretory proteins across the endoplasmic reticulum membrane by regulating which domains of the nascent polypeptide chain are visible to the cytosol during a translocational pause. [provided by RefSeq, Oct 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:13564698-13589910
Strand Reverse strand
Band A3
Transcripts
ENSMUST00000027068 ENSMUSP00000027068
ENSMUST00000185447
ENSMUST00000188377 ENSMUSP00000140499
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0015031 protein transport
Cellular Component
GO:0005575 cellular_component
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000067167
View Gene Order
ENSBTAG00000007562
Not yet available
Pathways
NETPATH
REACTOME
REACT_254308
Translation pathway
REACT_247926
Metabolism of proteins pathway
REACT_196445
SRP-dependent cotranslational protein targeting to membrane pathway
REACT_233572
Gene Expression pathway
KEGG
mmu04141
Protein processing in endoplasmic reticulum pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_115902
SRP-dependent cotranslational protein targeting to membrane pathway
REACT_1014
Translation pathway
REACT_17015
Metabolism of proteins pathway
REACT_71
Gene Expression pathway
KEGG
hsa04141
Protein processing in endoplasmic reticulum pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 72265
UniGene
RefSeq NM_028173
OMIM
CCDS CCDS14822
HPRD
IMGT
MGI ID MGI:1919515
MGI Symbol Tram1
EMBL
GenPept
RNA Seq Atlas 72265

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca